RETROSPECTIVE ANALYSIS OF ANAESTHETICS RECEIVED BY PATIENTS BEFORE SUSCEPTIBILITY TO MALIGNANT HYPERPYREXIA WAS RECOGNIZED
نویسندگان
چکیده
منابع مشابه
Identification of susceptibility to malignant hyperpyrexia in swine.
In vitro muscle contracture responses in swine susceptible to malignant hyperpyrexia (MH) were similar to those found in muscle from humans susceptible to this anaesthetic complication, confirming the suitability of the pig as an animal model for studying MH. The results suggest that there are different degrees of susceptibility to MH. Whichever drug was used, there was some overlap in the cont...
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A Caucasian male child aged 3 years, weighing 15 kg, was admitted for elective removal of a bind terminal phalanx of the right thumb. He had been a healthy child and had had no previous anaesthesia. He was apyrexial on admission (36.6°C) and again on the following day when surgery was to be performed. Routine examination by two anaesthetists revealed no clinical abnormality. A dose of 12 ml (72...
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The caffeine contracture of normal human muscle, which has been used as a model for malignant hyperpyrexia, is greatly potentiated by halothane. Prior administration of procaine markedly reduces the halothane-potentiated caffeine contracture, and procaine given at the height of the contracture induces relaxation. Lignocaine, on the other hand, produces a variable response and sometimes increase...
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detected in any patient by this method. Fourteen patients had raised serum creatine kinase activity (up to 5000 IU/1, normal range < 170 lU/i) and raised serum aspartate transaminase activity (up to 150 IU/1, normal < 35 IU/1). In all cases enzyme activity fell after admission to hospital. Peak serum creatine kinase activity was not significantly related to weight, sex, level of consciousness, ...
متن کاملMalignant hyperpyrexia: A dread complication
We are, indeed, fortunate in the Anesthesia Department at North Carolina Baptist Hospital to have an excellent supply of equipment. Yet, we are guilty, at times, of failing to take full advantage of it. A prime example is the temperature probe, a valuable aid in the diagnosis of malignant hyperpyrexia. In fact, it is so important that failure to monitor body temperature during anesthesia may ha...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1979
ISSN: 0007-0912
DOI: 10.1093/bja/51.10.949